UJI AKTIVITAS ANTIBAKTERI DARI EKSTRAK HEKSAN, EKSTRAK ETIL ASETAT DAN EKSTRAK ETANOL DAUN MINDI (Melia azedarach L.) TERHADAP BAKTERI Vibrio cholerae.

SIRAIT, HOTNAULI (2016) UJI AKTIVITAS ANTIBAKTERI DARI EKSTRAK HEKSAN, EKSTRAK ETIL ASETAT DAN EKSTRAK ETANOL DAUN MINDI (Melia azedarach L.) TERHADAP BAKTERI Vibrio cholerae. Diploma thesis, UNIVERSITAS 17 AGUSTUS 1945 JAKARTA.

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Abstract

Mindi (Melia azedarach L.) is a Meliaceae family plant which is known to have high potential as pesticides and natural antibacterial (Kardinan, 2003). This study aims to determine the antibacterial activity of hexane extract, ethyl acetate extract and ethanol extract of mindi leaf (Melia azedarach L.) against Vibrio cholera bacteria. Mindi leaf (Melia azedarach L.) was macerated using hexane, ethyl acetate and ethanol solvent. The extract obtained was tested for antibacterial activity by disc method. The study group was divided into 7 groups with 5 replicates, i.e KKP, KKN, KE1, KE2, KE3, KE4 and KE5. Data in the form of inhibition zone around the disc was statistically analyzed using ANOVA. From the results of the study found that at 100% concentration, hexane extract of mindi leaf has inhibitory zone of 17.28 mm, ethyl acetate extract of mindi leaf has inhibitory zone of 11.84 mm and ethanol extract of mindi leaf has inhibitory zone of 12.2 mm. Inhibition zone is still far compared to the KKP. Keywords: mindi leaf (Melia azedarach L.), Vibrio cholerae, antibacterial.

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